Lineage tracing of human B cells reveals the in vivo landscape of human antibody class switching

Lineage tracing of human B cells reveals the in vivo landscape of human antibody class switching

Antibody class switching is a feature of the adaptive immune system which enables diversification of the effector properties of antibodies. Even though class switching is essential for mounting a protective response to pathogens, the in vivo patterns and lineage characteristics of antibody class swi...

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Bibliographic Details
Main Authors: Felix Horns, Christopher Vollmers, Derek Croote, Sally F Mackey, Gary E Swan, Cornelia L Dekker, Mark M Davis, Stephen R Quake
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-08-01
Series:eLife
Subjects:
antibody
class switching
repertoire
cell decisions
Online Access:https://elifesciences.org/articles/16578

Internet

https://elifesciences.org/articles/16578

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