Taxifolin as a Metallo-β-Lactamase Inhibitor in Combination with Augmentin against Verona Imipenemase 2 Expressing <i>Pseudomonas aeruginosa</i>

Taxifolin as a Metallo-β-Lactamase Inhibitor in Combination with Augmentin against Verona Imipenemase 2 Expressing <i>Pseudomonas aeruginosa</i>

Among the various mechanisms that bacteria use to develop antibiotic resistance, the multiple expression of β-lactamases is particularly problematic, threatening public health and increasing patient mortality rates. Even if a combination therapy—in which a β-lactamase inhibitor is administered toget...

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Bibliographic Details
Main Authors: Bogdan M. Benin, Trae Hillyer, Aylin S. Crugnale, Andrew Fulk, Caitlyn A. Thomas, Michael W. Crowder, Matthew A. Smith, Woo Shik Shin
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Microorganisms
Subjects:
metallo-β-lactamases
computer-aided drug design
natural products
flavonol
taxifolin
quercetin
Online Access:https://www.mdpi.com/2076-2607/11/11/2653

Internet

https://www.mdpi.com/2076-2607/11/11/2653

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