Appropriate Delivery of the CRISPR/Cas9 System through the Nonlysosomal Route: Application for Therapeutic Gene Editing

Appropriate Delivery of the CRISPR/Cas9 System through the Nonlysosomal Route: Application for Therapeutic Gene Editing

Abstract The development of gene delivery has attracted increasing attention, especially when the introduction and application of the CRISPR/Cas9 gene editing system appears promising for gene therapy. However, ensuring biosafety and high gene editing efficiency at the same time poses a great challe...

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Bibliographic Details
Main Authors: Hang Yin, Xiaoling Yuan, Lihua Luo, Yichao Lu, Bing Qin, Junlei Zhang, Yingying Shi, Chunqi Zhu, Jie Yang, Xiang Li, Mengshi Jiang, Zhenyu Luo, Xinyu Shan, Dawei Chen, Jian You
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Advanced Science
Subjects:
CDC6
CRISPR/Cas9
endoplasmic reticulum
gene editing
pardaxin
Online Access:https://doi.org/10.1002/advs.201903381

Internet

https://doi.org/10.1002/advs.201903381

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