Atypical Scrapie Prions from Sheep and Lack of Disease in Transgenic Mice Overexpressing Human Prion Protein

Atypical Scrapie Prions from Sheep and Lack of Disease in Transgenic Mice Overexpressing Human Prion Protein

Public and animal health controls to limit human exposure to animal prions are focused on bovine spongiform encephalopathy (BSE), but other prion strains in ruminants may also have zoonotic potential. One example is atypical/Nor98 scrapie, which evaded statutory diagnostic methods worldwide until th...

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Bibliographic Details
Main Authors: Jonathan D.F. Wadsworth, Susan Joiner, Jacqueline M. Linehan, Anne Balkema-Buschmann, John Spiropoulos, Marion M. Simmons, Peter C. Griffiths, Martin H. Groschup, James Hope, Sebastian Brandner, Emmanuel A. Asante, John Collinge
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2013-11-01
Series:Emerging Infectious Diseases
Subjects:
Atypical scrapie
bovine spongiform encephalopathy
BSE
Nor98 scrapie
prions
prion disease
Online Access:https://wwwnc.cdc.gov/eid/article/19/11/12-1341_article

Internet

https://wwwnc.cdc.gov/eid/article/19/11/12-1341_article

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