Polyethylene glycol fusion repair of severed sciatic nerves accelerates recovery of nociceptive sensory perceptions in male and female rats of different strains

Polyethylene glycol fusion repair of severed sciatic nerves accelerates recovery of nociceptive sensory perceptions in male and female rats of different strains

Successful polyethylene glycol fusion (PEG-fusion) of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to: (1) rapidly restore electrophysiological continuity; (2) prevent distal Wallerian Degeneration and maintain their myelin sheaths; (3) promote primarily mo...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Liwen Zhou, Karthik Venkudusamy, Emily A. Hibbard, Yessenia Montoya, Alexa Olivarez, Cathy Z. Yang, Adelaide Leung, Varun Gokhale, Guhan Periyasamy, Zeal Pathak, Dale R. Sengelaub, George D. Bittner
Format: Artikel
Sprache:English
Veröffentlicht: Wolters Kluwer Medknow Publications 2025-09-01
Schriftenreihe:Neural Regeneration Research
Schlagworte:
autophagia
axotomy
collateral sprouting
neuropathic pain
peripheral nerve repair
polyethylene glycol fusion (peg-fusion)
saphenous nerve
sensory neurons
sex and strain
wallerian degeneration
Online Zugang:https://journals.lww.com/10.4103/NRR.NRR-D-23-01846

Online

https://journals.lww.com/10.4103/NRR.NRR-D-23-01846

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