Immunophenotype of T Cells Expressing Programmed Death-1 and Cytotoxic T Cell Antigen-4 in Early Lung Cancer: Local vs. Systemic Immune Response

The overexpression of programmed death-1 (PD-1) and cytotoxic T cell antigen 4 (CTLA-4) receptors on T cells are among the major mechanisms of tumor immunoevasion. However, the expression pattern of these receptors on T cell subpopulations of a different activation status and at different sites is p...

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Bibliographic Details
Main Authors: Iwona Kwiecien, Tomasz Skirecki, Małgorzata Polubiec-Kownacka, Agata Raniszewska, Joanna Domagala-Kulawik
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/4/567