Understanding the contributions of VPS35 and the retromer in neurodegenerative disease

Perturbations of the endolysosomal pathway have been suggested to play an important role in the pathogenesis of several neurodegenerative diseases, including Parkinson's disease (PD) and Alzheimer's disease (AD). Specifically, VPS35 and the retromer complex play an important role in the en...

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Bibliographic Details
Main Authors: Erin T. Williams, Xi Chen, P. Anthony Otero, Darren J. Moore
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122001607