Synthesis and anaigetical activity of derivatives of 1-indolilethil-3-pirrolin-2-ones

Interaction of methyl esters of acylpyruvic acides with mixture of aromatic aldehyde and tryptamine or 5-methoxytryptamine leads to 5-aryl-4-acyl-3-hydroxy-1-[2-(3-indolil)-ethyl)-2,5-dihydropyrrol-2-ones (I). The compounds (I) were transformed to 3,4-diaryl-1,4,5,6-tetrahydro-6-oxo-5-(2-(3-indolil)...

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Bibliographic Details
Main Authors: N V Dozmorova, V L Gein, N N Kasimova, L I Varkentin, B Ya Syropyatov, N V Danilova
Format: Article
Language:English
Published: Peoples’ Friendship University of Russia (RUDN University) 2009-12-01
Series:RUDN Journal of Medicine
Subjects:
Online Access:http://journals.rudn.ru/medicine/article/view/2514