Influenza Virus-Induced Oxidized DNA Activates Inflammasomes

Influenza Virus-Induced Oxidized DNA Activates Inflammasomes

Summary: Influenza virus M2 and PB1-F2 proteins have been proposed to activate the Nod-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome in macrophages by altering intracellular ionic balance or mitochondrial reactive oxygen species (ROS) production. However, the precise mechanism...

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Bibliographic Details
Main Authors: Miyu Moriyama, Minami Nagai, Yuhei Maruzuru, Takumi Koshiba, Yasushi Kawaguchi, Takeshi Ichinohe
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Immunology
Viral Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220304569

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http://www.sciencedirect.com/science/article/pii/S2589004220304569

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