Jinmaitong Alleviates Diabetic Neuropathic Pain Through Modulation of NLRP3 Inflammasome and Gasdermin D in Dorsal Root Ganglia of Diabetic Rats

Jinmaitong Alleviates Diabetic Neuropathic Pain Through Modulation of NLRP3 Inflammasome and Gasdermin D in Dorsal Root Ganglia of Diabetic Rats

Jinmaitong (JMT) is a compound prescription of traditional Chinese medicine that has been used to treat diabetic neuropathic pain (DNP) for many years. Here, we investigated the effects of JMT on the activation of NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome and pyroptosis...

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Bibliographic Details
Main Authors: Qing Sun, Rui Zhang, Xiaowei Xue, Qunli Wu, Dan Yang, Chao Wang, Bin Yan, Xiaochun Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
traditional Chinese medicine
pyroptosis
NLRP3 inflammasome
jinmaitong
diabetic neuropathic pain
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.679188/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.679188/full

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