Preoperative Intensified Chemoradiation with Intensity-Modulated Radiotherapy and Simultaneous Integrated Boost Combined with Capecitabine in Locally Advanced Rectal Cancer: Long-Term Outcomes of a Real-Life Multicenter Study

Preoperative Intensified Chemoradiation with Intensity-Modulated Radiotherapy and Simultaneous Integrated Boost Combined with Capecitabine in Locally Advanced Rectal Cancer: Long-Term Outcomes of a Real-Life Multicenter Study

Background: Despite the feasibility and promising activity data on intensity-modulated RT and simultaneous integrated boost (IMRT-SIB) dose escalation in preoperative chemoradiation (CRT) for locally advanced rectal cancer (LARC), few data are currently available on long-term outcomes. Patients and...

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Bibliographic Details
Main Authors: Marco Lupattelli, Elisa Palazzari, Jerry Polesel, Giuditta Chiloiro, Ilaria Angelicone, Valeria Panni, Luciana Caravatta, Saide Di Biase, Gabriella Macchia, Rita Marina Niespolo, Pierfrancesco Franco, Valeria Epifani, Elisa Meldolesi, Flavia de Giacomo, Marco Lucarelli, Giampaolo Montesi, Giovanna Mantello, Roberto Innocente, Mattia Falchetto Osti, Maria Antonietta Gambacorta, Cynthia Aristei, Antonino De Paoli
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cancers
Subjects:
rectal cancer
preoperative chemoradiotherapy (CRT)
intensity modulated RT (IMRT)
simultaneous integrated boost (SIB)
real-life clinical practice
radiotherapy dose
Online Access:https://www.mdpi.com/2072-6694/15/23/5702

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https://www.mdpi.com/2072-6694/15/23/5702

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