Histone locus bodies: a paradigm for how nuclear biomolecular condensates control cell cycle regulated gene expression

ABSTRACTHistone locus bodies (HLBs) are biomolecular condensates that assemble at replication-dependent (RD) histone genes in animal cells. These genes produce unique mRNAs that are not polyadenylated and instead end in a conserved 3’ stem loop critical for coordinated production of histone proteins...

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Bibliographic Details
Main Authors: Mark S. Geisler, James P. Kemp, Robert J. Duronio
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Nucleus
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19491034.2023.2293604