Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection

Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection

Mikaeloff et al. use untargeted and targeted LC-MS/MS-based plasma metabolic profiling to discover dysregulated metabolism including that of glutaminolysis in individuals living with HIV. Furthermore, decreased levels of neurosteroids were detected suggesting a potential connection between HIV and n...

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Bibliographic Details
Main Authors: Flora Mikaeloff, Sara Svensson Akusjärvi, George Mondinde Ikomey, Shuba Krishnan, Maike Sperk, Soham Gupta, Gustavo Daniel Vega Magdaleno, Alejandra Escós, Emilia Lyonga, Marie Claire Okomo, Claude Tayou Tagne, Hemalatha Babu, Christian L. Lorson, Ákos Végvári, Akhil C. Banerjea, Julianna Kele, Luke Elizabeth Hanna, Kamal Singh, João Pedro de Magalhães, Rui Benfeitas, Ujjwal Neogi
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02985-3

Internet

https://doi.org/10.1038/s42003-021-02985-3

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