Metabolic control by S6 kinases depends on dietary lipids.

Targeted deletion of S6 kinase (S6K) 1 in mice leads to higher energy expenditure and improved glucose metabolism. However, the molecular mechanisms controlling these effects remain to be fully elucidated. Here, we analyze the potential role of dietary lipids in regulating the mTORC1/S6K system. Ana...

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Bibliographic Details
Main Authors: Tamara R Castañeda, William Abplanalp, Sung Hee Um, Paul T Pfluger, Brigitte Schrott, Kimberly Brown, Erin Grant, Larissa Carnevalli, Stephen C Benoit, Donald A Morgan, Dean Gilham, David Y Hui, Kamal Rahmouni, George Thomas, Sara C Kozma, Deborah J Clegg, Matthias H Tschöp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3296718?pdf=render