PREPERATION AND CHARACTERIZATION OF β-CYCLODEXTRIN INCLUSION COMPLEXES ORAL TABLETS CONTAINING POORLY WATER SOLUBLE GLIMIPIRIDE USING FREEZE DRYING METHOD

limepiride is an oral antidiabetic drugs which is practically insoluble in water. The formation of β-cyclodextrin inclusion complex was able to increase the solubility of glimepiride. This study aim to prepare, characterize and formulation of inclusion complex tablets in order to meet the requiremen...

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Bibliographic Details
Main Authors: Yandi Syukri*, Laryssa Fernenda, issy Rizki Utami, Isna Qiftayati, Aris Perdana Kusuma, Rochmy Istikaharah
Format: Article
Language:English
Published: Universitas Gadjah Mada 2015-05-01
Series:Indonesian Journal of Pharmacy
Subjects:
Online Access:http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/779