Rockfish: A transformer-based model for accurate 5-methylcytosine prediction from nanopore sequencing

Abstract DNA methylation plays an important role in various biological processes, including cell differentiation, ageing, and cancer development. The most important methylation in mammals is 5-methylcytosine mostly occurring in the context of CpG dinucleotides. Sequencing methods such as whole-genom...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Dominik Stanojević, Zhe Li, Sara Bakić, Roger Foo, Mile Šikić
التنسيق: مقال
اللغة:English
منشور في: Nature Portfolio 2024-07-01
سلاسل:Nature Communications
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-024-49847-0