Rockfish: A transformer-based model for accurate 5-methylcytosine prediction from nanopore sequencing
Abstract DNA methylation plays an important role in various biological processes, including cell differentiation, ageing, and cancer development. The most important methylation in mammals is 5-methylcytosine mostly occurring in the context of CpG dinucleotides. Sequencing methods such as whole-genom...
المؤلفون الرئيسيون: | , , , , |
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التنسيق: | مقال |
اللغة: | English |
منشور في: |
Nature Portfolio
2024-07-01
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سلاسل: | Nature Communications |
الوصول للمادة أونلاين: | https://doi.org/10.1038/s41467-024-49847-0 |