Sustained postconfluent culture of human mammary epithelial cells enriches for luminal and c-Kit+ subtypes

Abstract Background A challenge in human mammary epithelial cell (HMEC) culture is sustaining the representation of competing luminal, myoepithelial, and progenitor lineages over time. As cells replicate in culture, myoepithelial cells come to dominate the composition of the culture with serial pass...

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Bibliographic Details
Main Authors: Michael E. Todhunter, Masaru Miyano, Eric G. Carlson, Stefan Hinz, Mark A. LaBarge
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Breast Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13058-022-01595-z