Sustained postconfluent culture of human mammary epithelial cells enriches for luminal and c-Kit+ subtypes
Abstract Background A challenge in human mammary epithelial cell (HMEC) culture is sustaining the representation of competing luminal, myoepithelial, and progenitor lineages over time. As cells replicate in culture, myoepithelial cells come to dominate the composition of the culture with serial pass...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-01-01
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Series: | Breast Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13058-022-01595-z |