Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival.

Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival.

Tobacco smoking is responsible for over 90% of lung cancer cases, and yet the precise molecular alterations induced by smoking in lung that develop into cancer and impact survival have remained obscure.We performed gene expression analysis using HG-U133A Affymetrix chips on 135 fresh frozen tissue s...

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Bibliographic Details
Main Authors: Maria Teresa Landi, Tatiana Dracheva, Melissa Rotunno, Jonine D Figueroa, Huaitian Liu, Abhijit Dasgupta, Felecia E Mann, Junya Fukuoka, Megan Hames, Andrew W Bergen, Sharon E Murphy, Ping Yang, Angela C Pesatori, Dario Consonni, Pier Alberto Bertazzi, Sholom Wacholder, Joanna H Shih, Neil E Caporaso, Jin Jen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2249927?pdf=render

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http://europepmc.org/articles/PMC2249927?pdf=render

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