Characterization of putative cholesterol recognition/interaction amino acid consensus-like motif of Campylobacter jejuni cytolethal distending toxin C.

Cytolethal distending toxin (CDT) produced by Campylobacter jejuni comprises a heterotrimeric complex formed by CdtA, CdtB, and CdtC. Among these toxin subunits, CdtA and CdtC function as essential proteins that mediate toxin binding to cytoplasmic membranes followed by delivery of CdtB into the nuc...

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Bibliographic Details
Main Authors: Chih-Ho Lai, Cheng-Kuo Lai, Ying-Ju Lin, Chiu-Lien Hung, Chia-Han Chu, Chun-Lung Feng, Chia-Shuo Chang, Hong-Lin Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3675143?pdf=render