Rational Design, Synthesis and Biological Evaluation of Novel Pyrazoline-Based Antiproliferative Agents in MCF-7 Cancer Cells

Breast cancer is a disease in which cells in the breast divide continuously without control. There are great limitations in cancer chemotherapy. Hence, it is essential to search for new cancer therapeutics. Herein, a novel series of EGFR/HER2 dual inhibitors has been designed based on the hybridizat...

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Bibliographic Details
Main Authors: Mariam M. Fakhry, Kazem Mahmoud, Mohamed S. Nafie, Ahmad O. Noor, Rawan H. Hareeri, Ismail Salama, Safaa M. Kishk
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/15/10/1245