Elevated sperm DNA fragmentation is correlated with an increased chromosomal aneuploidy rate of miscarried conceptus in women of advanced age undergoing fresh embryo transfer cycle

Elevated sperm DNA fragmentation is correlated with an increased chromosomal aneuploidy rate of miscarried conceptus in women of advanced age undergoing fresh embryo transfer cycle

BackgroundMale sperm DNA fragmentation (SDF) may be associated with assisted reproductive technology (ART) outcomes, but the impact of SDF on the occurrence of aneuploid-related miscarriage remains controversial.MethodsGenome-wide single-nucleotide polymorphism-based chromosomal microarray analysis...

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Bibliographic Details
Main Authors: Wanting Fu, Qiuying Cui, Zhiqin Bu, Hao Shi, Qingling Yang, Linli Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Endocrinology
Subjects:
sperm DNA fragmentation
chromosomal abnormality
miscarriage
chromosomal microarray analysis
assisted reproductive technology
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1289763/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2024.1289763/full

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