Thioredoxin-1 decreases alpha-synuclein induced by MPTP through promoting autophagy-lysosome pathway
Abstract Parkinson’s disease (PD) is characterized by the formation of Lewy body in dopaminergic neurons in the substantia nigra pars compacta (SNpc). Alpha-synuclein (α-syn) is a major component of Lewy body. Autophagy eliminates damaged organelles and abnormal aggregated proteins. Thioredoxin-1 (T...
| Κύριοι συγγραφείς: | , , , , , , , , , , |
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| Μορφή: | Άρθρο |
| Γλώσσα: | English |
| Έκδοση: |
Nature Publishing Group
2024-02-01
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| Σειρά: | Cell Death Discovery |
| Διαθέσιμο Online: | https://doi.org/10.1038/s41420-024-01848-0 |