Optimization of multi flow rate loading strategy for process intensification of Protein A chromatography

Monoclonal antibody (mAb) is a widely used therapeutic modality that is being used for treatment of chronic diseases like cancer, psoriasis, and other auto immune diseases. The affordability of these therapeutics is presently low because of their high manufacturing cost. Protein A chromatography ste...

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Bibliographic Details
Main Authors: Anjali Ramakrishna, Vijay Maranholkar, Sandeep Hadpe, Jyoti Iyer, Anurag Rathore
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Chromatography Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772391722000202