Effect of Structural Changes Induced by Deletion of <sup>54</sup>FLRAPSWF<sup>61</sup> Sequence in αB-crystallin on Chaperone Function and Anti-Apoptotic Activity

Previously, we showed that the removal of the 54–61 residues from αB-crystallin (αBΔ54–61) results in a fifty percent reduction in the oligomeric mass and a ten-fold increase in chaperone-like activity. In this study, we investigated the oligomeric organization changes in the deletion mutant contrib...

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Bibliographic Details
Main Authors: Sundararajan Mahalingam, Srabani Karmakar, Puttur Santhoshkumar, Krishna K. Sharma
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/19/10771