Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1.
An ability to sense pathogens by a number of specialized cell types including the dendritic cells plays a central role in host's defenses. Activation of these cells through the stimulation of the pathogen-recognition receptors induces the production of a number of cytokines including Type I int...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-06-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC3111542?pdf=render |