Phenotypic screening of signaling motifs that efficiently induce cell proliferation

Abstract Since cell proliferation is one of the fundamental cell fates, artificial control of cell proliferation based on a receptor-engineering approach is increasingly important in therapeutic and industrial applications. Since the signal transduction properties of cytokine receptors are greatly i...

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Bibliographic Details
Main Authors: Kirato Umene, Teruyuki Nagamune, Masahiro Kawahara
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42378-6