Reprogrammed siTNFα/neutrophil cytopharmaceuticals targeting inflamed joints for rheumatoid arthritis therapy

Reprogrammed siTNFα/neutrophil cytopharmaceuticals targeting inflamed joints for rheumatoid arthritis therapy

Rheumatoid arthritis (RA) is an autoimmune disease characterized by severe synovial inflammation and cartilage damage. Despite great progress in RA therapy, there still lacks the drugs to completely cure RA patients. Herein, we propose a reprogrammed neutrophil cytopharmaceuticals loading with TNFα-...

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Bibliographic Details
Main Authors: Yijun Chen, Kaiming Li, Mengying Jiao, Yingshuang Huang, Zihao Zhang, Lingjing Xue, Caoyun Ju, Can Zhang
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Neutrophil cytopharmaceuticals
siRNA
Macrophages
Rheumatoid arthritis
Tumor necrosis factor α
Gene delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S221138352200363X

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http://www.sciencedirect.com/science/article/pii/S221138352200363X

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