Vitamin D3 and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY trial): study protocol for a randomised placebo-controlled trial

Vitamin D3 and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY trial): study protocol for a randomised placebo-controlled trial

Abstract Background Of the 2 million children living with HIV globally, 90% live in sub-Saharan Africa. Despite antiretroviral therapy, longstanding HIV infection is associated with several chronic complications in children including growth failure, particularly stunting and delayed puberty. Vitamin...

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Bibliographic Details
Main Authors: Nyasha Veronica Dzavakwa, Molly Chisenga, Grace McHugh, Suzanne Filteau, Celia Louise Gregson, Lackson Kasonka, Katharina Kranzer, Hildah Banda Mabuda, Hilda Mujuru, Nicol Redzo, Sarah Rowland-Jones, Ulrich E. Schaible, Victoria Simms, Rashida Abbas Ferrand, the VITALITY team
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Trials
Subjects:
Vitamin D3
Calcium carbonate
HIV
Bone density
Stunting
Pubertal delay
Online Access:https://doi.org/10.1186/s13063-021-05985-0

Internet

https://doi.org/10.1186/s13063-021-05985-0

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