Electroacupuncture Alleviates Depressive-like Behavior by Modulating the Expression of P2X7/NLRP3/IL-1β of Prefrontal Cortex and Liver in Rats Exposed to Chronic Unpredictable Mild Stress

Electroacupuncture Alleviates Depressive-like Behavior by Modulating the Expression of P2X7/NLRP3/IL-1β of Prefrontal Cortex and Liver in Rats Exposed to Chronic Unpredictable Mild Stress

Depression is a complex clinical disorder associated with poor outcomes. Electroacupuncture (EA) has been demonstrated to have an important role in both clinical and pre-clinical depression investigations. Evidence has suggested that the P2X7 receptor (P2X7R), NLRP3, and IL-1β play an important role...

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Bibliographic Details
Main Authors: Fang Pang, Yunhao Yang, Siqin Huang, Zhixue Yang, Zhengwei Zhu, Dongmei Liao, Xiao Guo, Min Zhou, Yi Li, Chenglin Tang
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Brain Sciences
Subjects:
depression
electroacupuncture
P2X7R/NLRP3/IL-1β
liver-brain axis
chronic unpredictable mild stress (CUMS)
behavior
Online Access:https://www.mdpi.com/2076-3425/13/3/436

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https://www.mdpi.com/2076-3425/13/3/436

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