Addressing Glutathione Redox Status in Clinical Samples by Two-Step Alkylation with N-ethylmaleimide Isotopologues

Determination of the ratio of reduced to oxidized glutathione is of profound clinical interest in assessing the oxidative status of tissues and body fluids. However, this ratio is not yet a routine clinical parameter due to the analytically challenging interconversion of reduced (free) glutathione t...

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Bibliographic Details
Main Authors: Tamara Tomin, Matthias Schittmayer, Ruth Birner-Gruenberger
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/10/2/71