Arf6-driven endocytic recycling of CD147 determines HCC malignant phenotypes

Arf6-driven endocytic recycling of CD147 determines HCC malignant phenotypes

Abstract Background Adhesion molecules distributed on the cell-surface depends upon their dynamic trafficking that plays an important role during cancer progression. ADP-ribosylation factor 6 (Arf6) is a master regulator of membrane trafficking. CD147, a tumor-related adhesive protein, can promote t...

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Bibliographic Details
Main Authors: Shanshan Qi, Linjia Su, Jing Li, Chuanshan Zhang, Zhe Ma, Guiqiu Liu, Qing Zhang, Guhe Jia, Yongjun Piao, Sihe Zhang
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Arf6
CD147
Endocytic recycling
Malignant phenotype
Liver cancer
Online Access:http://link.springer.com/article/10.1186/s13046-019-1464-9

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http://link.springer.com/article/10.1186/s13046-019-1464-9

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