Superior control of inflammatory pain by corticotropin-releasing factor receptor 1 via opioid peptides in distinct pain-relevant brain areas
Abstract Background Under inflammatory conditions, the activation of corticotropin-releasing factor (CRF) receptor has been shown to inhibit pain through opioid peptide release from immune cells or neurons. CRF’s effects on human and animal pain modulation depend, however, on the distribution of its...
主要な著者: | , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
BMC
2022-06-01
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シリーズ: | Journal of Neuroinflammation |
主題: | |
オンライン・アクセス: | https://doi.org/10.1186/s12974-022-02498-8 |