Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging

Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging

Abstract Background HIV infection is enhanced by cell adhesions that form between infected and uninfected T cells called virological synapses (VS). VS are initiated by an interaction between Env and CD4 on cell surfaces and result in the recruitment of virus assembly to the site of cell–cell contact...

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Bibliographic Details
Main Authors: Lili Wang, Sudeh Izadmehr, Edwin Kamau, Xiang-Peng Kong, Benjamin K. Chen
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Retrovirology
Subjects:
HIV-1
Virological synapse
Envelope protein
Gag
GFP
Online Access:http://link.springer.com/article/10.1186/s12977-019-0464-3

Internet

http://link.springer.com/article/10.1186/s12977-019-0464-3

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