The Effect of Intravenous Mannitol Combined With Normal Saline in Preventing Cisplatin-Induced Nephrotoxicity: A Randomized, Double-Blind, Placebo-Controlled Trial
PURPOSENephrotoxicity is a major dose-limiting toxicity among patients with cancer who were treated with cisplatin. Although no standard approach is available to prevent cisplatin-induced nephrotoxicity, administering intravenous isotonic saline is recommended. Additionally, mannitol combined with h...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Society of Clinical Oncology
2022-03-01
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Series: | JCO Global Oncology |
Online Access: | https://ascopubs.org/doi/10.1200/GO.21.00275 |