Construction of a recombinant vaccine expressing Nipah virus glycoprotein using the replicative and highly attenuated vaccinia virus strain LC16m8.

Construction of a recombinant vaccine expressing Nipah virus glycoprotein using the replicative and highly attenuated vaccinia virus strain LC16m8.

Nipah virus (NiV) is a highly pathogenic zoonotic virus that causes severe encephalitis and respiratory diseases and has a high mortality rate in humans (>40%). Epidemiological studies on various fruit bat species, which are natural reservoirs of the virus, have shown that NiV is widely distribut...

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Bibliographic Details
Main Authors: Shumpei Watanabe, Tomoki Yoshikawa, Yoshihiro Kaku, Takeshi Kurosu, Shuetsu Fukushi, Satoko Sugimoto, Yuki Nishisaka, Hikaru Fuji, Glenn Marsh, Ken Maeda, Hideki Ebihara, Shigeru Morikawa, Masayuki Shimojima, Masayuki Saijo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0011851

Internet

https://doi.org/10.1371/journal.pntd.0011851

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