The C-terminus of ClpC1 of Mycobacterium tuberculosis is crucial for its oligomerization and function.

Mycobacterium tuberculosis ClpC1 is a member of the Hsp100/Clp AAA+ family of ATPases. The primary sequence of ClpC1 contains two N-terminal domains and two nucleotide binding domains (NBD). The second NBD has a long C-terminal sub-domain containing several motifs important for substrate interaction...

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Bibliographic Details
Main Authors: Divya Bajaj, Janendra K Batra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527473?pdf=render