Aberrant Expression of Circulating MicroRNA Leads to the Dysregulation of Alpha-Synuclein and Other Pathogenic Genes in Parkinson’s Disease

Aberrant Expression of Circulating MicroRNA Leads to the Dysregulation of Alpha-Synuclein and Other Pathogenic Genes in Parkinson’s Disease

A group of circulating microRNAs (miRNAs) have been implicated in the pathogenesis of Parkinson’s disease. However, a comprehensive study of the interactions between pathogenic miRNAs and their downstream Parkinson’s disease (PD)-related target genes has not been performed. Here, we identified the m...

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Bibliographic Details
Main Authors: Meng Cai, Songshan Chai, Tao Xiong, Jun Wei, Weibing Mao, Yasha Zhu, Xiang Li, Wei Wei, Xuan Dai, Bangkun Yang, Wen Liu, Bing Shu, Mengyang Wang, Taojunjin Lu, Yuankun Cai, Zhixin Zheng, Zhimin Mei, Yixuan Zhou, Jingyi Yang, Jingwei Zhao, Lei Shen, Joshua Wing Kei Ho, Jincao Chen, Nanxiang Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
PD-related genes
alpha synuclein
microRNA
Parkinson’s disease
exosomes (EX)
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.695007/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.695007/full

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