Distinct hepatocyte identities in liver homeostasis and regenerationKey points

Distinct hepatocyte identities in liver homeostasis and regenerationKey points

Summary: The process of metabolic liver zonation is spontaneously established by assigning distributed tasks to hepatocytes along the porto-central blood flow. Hepatocytes fulfil critical metabolic functions, while also maintaining hepatocyte mass by replication when needed. Recent technological adv...

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Bibliographic Details
Main Authors: Feng Chen, Katharina Schönberger, Jan S. Tchorz
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:JHEP Reports
Subjects:
Liver regeneration
Hepatocyte identity
Hepatocyte plasticity
Ploidy
Liver stem cells
Metabolic liver zonation
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923001106

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http://www.sciencedirect.com/science/article/pii/S2589555923001106

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