Frequency of Pfcrt T76 and Pfdhfr Asn-108 Drug Resistance Mutations in falciparum Malaria in Southeastern Malaria Endemic Area of Iran

Background: Point mutations in the genes, Pfcrt and Pfdhfr, have been identified elsewhere as strongly associated with re­sistance to chloroquine (CQ) and pyrimethamine, respectively.  Methods: Using a restriction digestion method, we report the frequency of two important mutations, T76 and Asn108...

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Bibliographic Details
Main Authors: MR Razavi, SR Naddaf, JLe Bras, A Raesi, AR Esmaeili, M Assmar
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2008-03-01
Series:Iranian Journal of Public Health
Subjects:
Online Access:https://ijph.tums.ac.ir/index.php/ijph/article/view/2069