A Cell-Based Screen Identifies HDAC Inhibitors as Activators of RIG-I Signaling
Enhancing the immune microenvironment in cancer by targeting the nucleic acid sensors is becoming a potent therapeutic strategy. Among the nucleic acid sensors, activation of the RNA sensor Retinoic Acid-inducible Gene (RIG-I) using small hairpin RNAs has been shown to elicit powerful innate and ada...
| Glavni autori: | , , , , |
|---|---|
| Format: | Članak |
| Jezik: | English |
| Izdano: |
Frontiers Media S.A.
2022-02-01
|
| Serija: | Frontiers in Molecular Biosciences |
| Teme: | |
| Online pristup: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.837610/full |