Arylated analogues of cypronazole: fungicidal effect and activity on human fibroblasts. Docking analysis and molecular dynamics simulations

Arylated analogues of cypronazole: fungicidal effect and activity on human fibroblasts. Docking analysis and molecular dynamics simulations

Abstract Triadimefon (TDM) and cyproconazole (CPZ) are two triazoles widely used as fungicides. Several azoles were synthesised starting from commercial TDM and CPZ. The compounds were evaluated against phytopathogenic filamentous fungi, including Aspergillus fumigatus (AF), A. niger (AN), A. ustus...

Full description

Bibliographic Details
Main Authors: Natividad Herrera Cano, Sebastian A. Andujar, Cristina Theoduloz, Daniel A. Wunderlin, Ana N. Santiago, Guillermo Schmeda-Hirschmann, Ricardo D. Enriz, Gabriela E. Feresin
Format: Article
Language:English
Published: SpringerOpen 2022-03-01
Series:Natural Products and Bioprospecting
Subjects:
Azoles
Antifungal cytotoxicity
Conformational and electronic analysis
Online Access:https://doi.org/10.1007/s13659-022-00329-0

Internet

https://doi.org/10.1007/s13659-022-00329-0

Similar Items