Attenuated EAN in TNF-α deficient mice is associated with an altered balance of M1/M2 macrophages.

The role of tumor necrosis factor (TNF)-α and its receptors in neuroautoimmune and neuroinflammatory diseases has been controversial. On the basis of our previous studies, we hereby aimed to further clarify TNF-α's mechanism of action and to explore the potential role of TNF-α receptor (TNFR)1...

Full description

Bibliographic Details
Main Authors: Hong-Liang Zhang, Mohammed Y Hassan, Xiang-Yu Zheng, Sheikh Azimullah, Hernan Concha Quezada, Naheed Amir, Mohamed Elwasila, Eilhard Mix, Abdu Adem, Jie Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3364226?pdf=render