Enhancing the Therapeutic Efficacy of Bone Marrow-Derived Mononuclear Cells with Growth Factor-Expressing Mesenchymal Stem Cells for ALS in Mice

Enhancing the Therapeutic Efficacy of Bone Marrow-Derived Mononuclear Cells with Growth Factor-Expressing Mesenchymal Stem Cells for ALS in Mice

Summary: Several treatments have been attempted in amyotrophic lateral sclerosis (ALS) animal models and patients. Recently, transplantation of bone marrow-derived mononuclear cells (MNCs) was investigated as a regenerative therapy for ALS, but satisfactory treatments remain to be established. To de...

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Bibliographic Details
Main Authors: Tomoya Terashima, Shuhei Kobashi, Yasuhiro Watanabe, Mami Nakanishi, Naoto Honda, Miwako Katagi, Natsuko Ohashi, Hideto Kojima
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:iScience
Subjects:
Molecular Neuroscience
Cellular Neuroscience
Stem Cells Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220309615

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http://www.sciencedirect.com/science/article/pii/S2589004220309615

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