Role of the heparin-binding domain in intracellular trafficking of sHB-EGF

Heparin-binding EGF-like growth factor (HB-EGF) is a member of the epidermal growth factor fami­ly that was proven as a potent mitogen and chemoattractant. HB-EGF mediated EGFR activation is a key event in the stimulation of gene expression, cell migration and proliferation during both normal and pa...

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Bibliographic Details
Main Authors: O. I. Krynina, K. Yu. Manoilov, D. V. Kolybo, S. V. Komisarenko
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2019-08-01
Series:The Ukrainian Biochemical Journal
Subjects:
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2019/06/Krynina_4_19.pdf