Phenotypic Differences between Asian and African Lineage Zika Viruses in Human Neural Progenitor Cells

Phenotypic Differences between Asian and African Lineage Zika Viruses in Human Neural Progenitor Cells

ABSTRACT Recent Zika virus (ZIKV) infections have been associated with a range of neurological complications, in particular congenital microcephaly. Human neural progenitor cells (hNPCs) are thought to play an important role in the pathogenesis of microcephaly, and experimental ZIKV infection of hNP...

Full description

Bibliographic Details
Main Authors: Fatih Anfasa, Jurre Y. Siegers, Mark van der Kroeg, Noreen Mumtaz, V. Stalin Raj, Femke M. S. de Vrij, W. Widagdo, Gülsah Gabriel, Sara Salinas, Yannick Simonin, Chantal Reusken, Steven A. Kushner, Marion P. G. Koopmans, Bart Haagmans, Byron E. E. Martina, Debby van Riel
Format: Article
Language:English
Published: American Society for Microbiology 2017-08-01
Series:mSphere
Subjects:
African strains
Asian strains
growth kinetics
human neural progenitor cells
neuronal cells
one-step growth curve
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00292-17

Internet

https://journals.asm.org/doi/10.1128/mSphere.00292-17

Similar Items