PTP4A1 promotes oral squamous cell carcinoma (OSCC) metastasis through altered mitochondrial metabolic reprogramming

Abstract PTP4A1 (Protein tyrosine phosphatase 4A1) is a protein tyrosine phosphatase that regulates a range of pro-oncogenic signaling pathways. Here, we report a novel role for PTP4A1 in oral squamous cell carcinoma (OSCC) growth and development. We show that PTP4A1 is frequently overexpressed in O...

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Bibliographic Details
Main Authors: Bing Liu, Wen Si, Bo Wei, Xuan Zhang, Peng Chen
Format: Article
Language:English
Published: Nature Publishing Group 2023-09-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01657-x