Functional sensitivity and mutational robustness of proteins
Sensitivity and robustness appear to be contrasting concepts. However, natural proteins are robust enough to tolerate random mutations, meanwhile be susceptible enough to sense environmental signals, exhibiting both high functional sensitivity (i.e., plasticity) and mutational robustness. Uncovering...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
American Physical Society
2020-09-01
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Series: | Physical Review Research |
Online Access: | http://doi.org/10.1103/PhysRevResearch.2.033452 |