Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners

Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners

Endoglin is a 180-kDa glycoprotein receptor primarily expressed by the vascular endothelium and involved in cardiovascular disease and cancer. Heterozygous mutations in the endoglin gene (ENG) cause hereditary hemorrhagic telangiectasia type 1, a vascular disease that presents with nasal and gastroi...

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Bibliographic Details
Main Authors: Eunate Gallardo-Vara, Lidia Ruiz-Llorente, Juan Casado-Vela, María J. Ruiz-Rodríguez, Natalia López-Andrés, Asit K. Pattnaik, Miguel Quintanilla, Carmelo Bernabeu
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
endothelial cells
endoglin
TGF-β
BMP
HHT
cancer
preeclampsia
TRIM family
galectin family
protein–protein interactions
Online Access:https://www.mdpi.com/2073-4409/8/9/1082

Internet

https://www.mdpi.com/2073-4409/8/9/1082

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