Stearic Acid Serves as a Potent Inhibitor of Protein Tyrosine Phosphatase 1B

Stearic Acid Serves as a Potent Inhibitor of Protein Tyrosine Phosphatase 1B

Background/Aims: Free fatty acids (FFAs) are implicated in diverse signal transduction pathways. The present study investigated the effects of the saturated FFA stearic acid on protein tyrosine phosphatase 1B (PTP1B) activity, Akt activity, and glucose uptake into cells relevant to insulin signal. M...

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Bibliographic Details
Main Authors: Ayako Tsuchiya, Takeshi Kanno, Tomoyuki Nishizaki
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Akt
Glucose uptake
Stearic acid
Protein tyrosine phosphatase 1B
Insulin receptor
Online Access:http://www.karger.com/Article/FullText/356582

Internet

http://www.karger.com/Article/FullText/356582

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