The efficacy of exogenous melatonin supplement in ameliorating irritable bowel syndrome severity: A meta-analysis of randomized controlled trials

The efficacy of exogenous melatonin supplement in ameliorating irritable bowel syndrome severity: A meta-analysis of randomized controlled trials

Background: Irritable bowel syndrome (IBS) was found in 11% of the general population worldwide. The current pharmacologic management of IBS was unsatisfactory, and it was accompanied by a number of adverse events. Melatonin was found to play an important role in gastrointestinal smooth muscle motil...

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Main Authors: Keng-Hsu Chen, Bing-Yan Zeng, Bing-Syuan Zeng, Cheuk-Kwan Sun, Yu-Shian Cheng, Kuan-Pin Su, Yi-Cheng Wu, Tien-Yu Chen, Pao-Yen Lin, Chih-Sung Liang, Chih-Wei Hsu, Che-Sheng Chu, Yen-Wen Chen, Pin-Yang Yeh, Ming-Kung Wu, Ping-Tao Tseng, Chung-Yao Hsu
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Journal of the Formosan Medical Association
Subjects:
Irritable bowel syndrome
Melatonin
Gastroenterology
Meta-analysis
Circadian rhythm
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664622003850

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http://www.sciencedirect.com/science/article/pii/S0929664622003850

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